IGNITE: Model Systems for Neurotherapeutic Discovery (R61/R33, No Clinical Trials) Direct costs $499,000 per year and $750,000 total for the three-year project. - October 20, 2027 National Institutes of Health (NIH)-R61/R33 Exploratory/Developmental Phased Award* This NOFO funds animal or ex vivo models that mimic neurological disorders to improve translational relevance.